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Thyroxin Protects White Matter from Hypoxic-Ischemic Insult in the Immature Sprague–Dawley Rat Brain by Regulating Periventricular White Matter and Cortex BDNF and CREB Pathways

Background: Periventricular white-matter (WM) injury is a prominent feature of brain injury in preterm infants. Thyroxin (T4) treatment reduces the severity of hypoxic-ischemic (HI)-mediated WM injury in the immature brain. This study aimed to delineate molecular events underlying T4 protection foll...

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Detalles Bibliográficos
Autores principales: Hung, Pi-Lien, Hsu, Mei-Hsin, Yu, Hong-Ren, Wu, Kay L. H., Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164053/
https://www.ncbi.nlm.nih.gov/pubmed/30158497
http://dx.doi.org/10.3390/ijms19092573