The interleukin-27 -964A>G polymorphism enhances sepsis-induced inflammatory responses and confers susceptibility to the development of sepsis

BACKGROUND: Previous studies have identified critical roles of IL-27 in the pathological mechanisms of sepsis, and blockade of IL-27 may be a promising alternative therapy for sepsis. The purpose of this study was to evaluate the clinical relevance of IL-27 genetic polymorphisms in sepsis and to fur...

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Detalles Bibliográficos
Autores principales: He, Junbing, Zhang, Quanfu, Zhang, Wenying, Chen, Feng, Zhao, Tian, Lin, Yao, Li, Jia, Liu, Yansong, Liu, Yuchun, Shao, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164187/
https://www.ncbi.nlm.nih.gov/pubmed/30268141
http://dx.doi.org/10.1186/s13054-018-2180-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164187/
https://www.ncbi.nlm.nih.gov/pubmed/30268141
http://dx.doi.org/10.1186/s13054-018-2180-0

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