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Topical Plant Polyphenols Prevent Type I Interferon Signaling in the Skin and Suppress Contact Hypersensitivity

Human keratinocytes were recently shown to respond to anti-EGFR (epidermal growth factor receptor) drugs with activation of an interferon-κ-driven autocrine loop, leading to enhanced expression of innate antiviral effectors and of the pro-inflammatory chemokines CXCL10 (C-X-C motif chemokine 10) and...

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Detalles Bibliográficos
Autores principales: Carbone, Maria Luigia, Lulli, Daniela, Passarelli, Francesca, Pastore, Saveria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164211/
https://www.ncbi.nlm.nih.gov/pubmed/30200670
http://dx.doi.org/10.3390/ijms19092652