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Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides

Spider venoms are a rich source of insecticidal peptide toxins. Their development as bioinsecticides has, however, been hampered due to concerns about potential lack of stability and oral bioactivity. We therefore systematically evaluated several synthetic strategies to increase the stability and or...

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Detalles Bibliográficos
Autores principales: Herzig, Volker, de Araujo, Aline Dantas, Greenwood, Kathryn P., Chin, Yanni K.-Y., Windley, Monique J., Chong, Youmie, Muttenthaler, Markus, Mobli, Mehdi, Audsley, Neil, Nicholson, Graham M., Alewood, Paul F., King, Glenn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164231/
https://www.ncbi.nlm.nih.gov/pubmed/30154370
http://dx.doi.org/10.3390/biomedicines6030090