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Sesterterpenoid and Steroid Metabolites from a Deep-Water Alaska Sponge Inhibit Wnt/β-Catenin Signaling in Colon Cancer Cells

The Wnt/β-catenin signaling pathway is known to play critical roles in a wide range of cellular processes: cell proliferation, differentiation, migration and embryonic development. Importantly, dysregulation of this pathway is tightly associated with pathogenesis in most human cancers. Therefore, th...

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Detalles Bibliográficos
Autores principales: Park, Hyun Bong, Tuan, Nguyen Quoc, Oh, Joonseok, Son, Younglim, Hamann, Mark T., Stone, Robert, Kelly, Michelle, Oh, Sangtaek, Na, MinKyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164309/
https://www.ncbi.nlm.nih.gov/pubmed/30150508
http://dx.doi.org/10.3390/md16090297