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Dissolving Microneedle Patches for Transdermal Insulin Delivery in Diabetic Mice: Potential for Clinical Applications

In this study, dissolving polymeric microneedle (MN) patches composed of gelatin and sodium carboxymethyl cellulose (CMC) were used to localize insulin. Their in vitro skin insertion capabilities were determined using tissue-marking dye to stain the skin after patches removal. Scanning electron micr...

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Detalles Bibliográficos
Autores principales: Chen, Chih-Hao, Shyu, Victor Bong-Hang, Chen, Chien-Tzung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164338/
https://www.ncbi.nlm.nih.gov/pubmed/30189671
http://dx.doi.org/10.3390/ma11091625