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Dissolving Microneedle Patches for Transdermal Insulin Delivery in Diabetic Mice: Potential for Clinical Applications
In this study, dissolving polymeric microneedle (MN) patches composed of gelatin and sodium carboxymethyl cellulose (CMC) were used to localize insulin. Their in vitro skin insertion capabilities were determined using tissue-marking dye to stain the skin after patches removal. Scanning electron micr...
Autores principales: | Chen, Chih-Hao, Shyu, Victor Bong-Hang, Chen, Chien-Tzung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164338/ https://www.ncbi.nlm.nih.gov/pubmed/30189671 http://dx.doi.org/10.3390/ma11091625 |
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