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Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

Amyloids result from the aggregation of a set of diverse proteins, due to either specific mutations or promoting intra- or extra-cellular conditions. Structurally, they are rich in intermolecular β-sheets and are the causative agents of several diseases, both neurodegenerative and systemic. It is be...

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Detalles Bibliográficos
Autores principales: Giorgetti, Sofia, Greco, Claudio, Tortora, Paolo, Aprile, Francesco Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164555/
https://www.ncbi.nlm.nih.gov/pubmed/30205618
http://dx.doi.org/10.3390/ijms19092677