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Radiation Sensitization of Basal Cell and Head and Neck Squamous Cell Carcinoma by the Hedgehog Pathway Inhibitor Vismodegib

Vismodegib, an inhibitor of the Hedgehog signaling pathway, is an approved drug for monotherapy in locally advanced or metastatic basal cell carcinoma (BCC). Data on combined modality treatment by vismodegib and radiation therapy, however, are rare. In the present study, we examined the radiation se...

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Detalles Bibliográficos
Autores principales: Hehlgans, Stephanie, Booms, Patrick, Güllülü, Ömer, Sader, Robert, Rödel, Claus, Balermpas, Panagiotis, Rödel, Franz, Ghanaati, Shahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164565/
https://www.ncbi.nlm.nih.gov/pubmed/30142876
http://dx.doi.org/10.3390/ijms19092485