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Radiation Sensitization of Basal Cell and Head and Neck Squamous Cell Carcinoma by the Hedgehog Pathway Inhibitor Vismodegib
Vismodegib, an inhibitor of the Hedgehog signaling pathway, is an approved drug for monotherapy in locally advanced or metastatic basal cell carcinoma (BCC). Data on combined modality treatment by vismodegib and radiation therapy, however, are rare. In the present study, we examined the radiation se...
Autores principales: | Hehlgans, Stephanie, Booms, Patrick, Güllülü, Ömer, Sader, Robert, Rödel, Claus, Balermpas, Panagiotis, Rödel, Franz, Ghanaati, Shahram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164565/ https://www.ncbi.nlm.nih.gov/pubmed/30142876 http://dx.doi.org/10.3390/ijms19092485 |
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