Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways

Although cisplatin is a potent chemotherapeutic agent against cancers, its clinical application is seriously limited by its severe side effects of nephrotoxicity. Previous studies reported that saponins isolated from the roots of Platycodon grandiflorum (PGS) exerted protective effects in various an...

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Detalles Bibliográficos
Autores principales: Zhang, Weizhe, Hou, Jingang, Yan, Xiaotong, Leng, Jing, Li, Rongyan, Zhang, Jing, Xing, Jingjing, Chen, Chen, Wang, Zi, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164643/
https://www.ncbi.nlm.nih.gov/pubmed/30235825
http://dx.doi.org/10.3390/nu10091328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164643/
https://www.ncbi.nlm.nih.gov/pubmed/30235825
http://dx.doi.org/10.3390/nu10091328

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