Flavonoids as Putative Epi-Modulators: Insight into Their Binding Mode with BRD4 Bromodomains Using Molecular Docking and Dynamics

Flavonoids are widely recognized as natural polydrugs, given their anti-inflammatory, antioxidant, sedative, and antineoplastic activities. Recently, different studies showed that flavonoids have the potential to inhibit bromodomain and extraterminal (BET) bromodomains. Previous reports suggested th...

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Detalles Bibliográficos
Autores principales: Prieto-Martínez, Fernando D., Medina-Franco, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164663/
https://www.ncbi.nlm.nih.gov/pubmed/30041464
http://dx.doi.org/10.3390/biom8030061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164663/
https://www.ncbi.nlm.nih.gov/pubmed/30041464
http://dx.doi.org/10.3390/biom8030061

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