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A Fluorescent Cy7-Mercaptopyridine for the Selective Detection of Glutathione over Homocysteine and Cysteine

We describe a near-infrared (NIR) fluorescent probe 1 for the selective detection of GSH over Hcy and Cys under physiological conditions. Probe 1 was composed of Cy7 as a NIR dye and 2-mercaptopyridine as a GSH-reactive site and fluorescence quencher. In the presence of GSH, the 2-mercaptopyridine f...

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Detalles Bibliográficos
Autores principales: Yoon, Shin A, Kim, Wantae, Sharma, Amit, Verwilst, Peter, Won, Miae, Lee, Min Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164685/
https://www.ncbi.nlm.nih.gov/pubmed/30200477
http://dx.doi.org/10.3390/s18092897