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Proteasome-Rich PaCS as an Oncofetal UPS Structure Handling Cytosolic Polyubiquitinated Proteins. In Vivo Occurrence, in Vitro Induction, and Biological Role

In this article, we outline and discuss available information on the cellular site and mechanism of proteasome interaction with cytosolic polyubiquitinated proteins and heat-shock molecules. The particulate cytoplasmic structure (PaCS) formed by barrel-like particles, closely reproducing in vivo the...

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Detalles Bibliográficos
Autores principales: Solcia, Enrico, Necchi, Vittorio, Sommi, Patrizia, Ricci, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164709/
https://www.ncbi.nlm.nih.gov/pubmed/30223470
http://dx.doi.org/10.3390/ijms19092767