siRNAs Targeting Growth Factor Receptor and Anti-Apoptotic Genes Synergistically Kill Breast Cancer Cells through Inhibition of MAPK and PI-3 Kinase Pathways

Breast cancer, the second leading cause of female deaths worldwide, is usually treated with cytotoxic drugs, accompanied by adverse side-effects, development of chemoresistance and relapse of disease condition. Survival and proliferation of the cancer cells are greatly empowered by over-expression o...

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Detalles Bibliográficos
Autores principales: Kamaruzman, Nur Izyani, Tiash, Snigdha, Ashaie, Maeirah, Chowdhury, Ezharul Hoque
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164725/
https://www.ncbi.nlm.nih.gov/pubmed/29932151
http://dx.doi.org/10.3390/biomedicines6030073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164725/
https://www.ncbi.nlm.nih.gov/pubmed/29932151
http://dx.doi.org/10.3390/biomedicines6030073

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