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Co(II)(Chromomycin)(2) Complex Induces a Conformational Change of CCG Repeats from i-Motif to Base-Extruded DNA Duplex

We have reported the propensity of a DNA sequence containing CCG repeats to form a stable i-motif tetraplex structure in the absence of ligands. Here we show that an i-motif DNA sequence may transition to a base-extruded duplex structure with a GGCC tetranucleotide tract when bound to the (Co(II))-m...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Wen, Satange, Roshan, Wu, Pei-Ching, Jhan, Cyong-Ru, Chang, Chung-ke, Chung, Kuang-Ren, Waring, Michael J., Lin, Sheng-Wei, Hsieh, Li-Ching, Hou, Ming-Hon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164834/
https://www.ncbi.nlm.nih.gov/pubmed/30227633
http://dx.doi.org/10.3390/ijms19092796