Molecular Dynamics Exploration of Selectivity of Dual Inhibitors 5M7, 65X, and 65Z toward Fatty Acid Binding Proteins 4 and 5

Designing highly selective inhibitors of fatty acid binding proteins 4 and 5 (FABP4 and FABP5) is of importance for treatment of some diseases related with inflammation, metabolism, and tumor growth. In this study, molecular dynamics (MD) simulations combined with molecular mechanics generalized Bor...

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Detalles Bibliográficos
Autores principales: Yan, Fangfang, Liu, Xinguo, Zhang, Shaolong, Su, Jing, Zhang, Qinggang, Chen, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164837/
https://www.ncbi.nlm.nih.gov/pubmed/30142969
http://dx.doi.org/10.3390/ijms19092496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164837/
https://www.ncbi.nlm.nih.gov/pubmed/30142969
http://dx.doi.org/10.3390/ijms19092496

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