Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides

Fibrosis results from the excessive accumulation of extracellular matrix in chronically injured tissue. The fibrotic process is governed by crosstalk between many signaling pathways. The search for an effective treatment is further complicated by the fact that there is a degree of tissue-specificity...

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Detalles Bibliográficos
Autores principales: March, James T., Golshirazi, Golnoush, Cernisova, Viktorija, Carr, Heidi, Leong, Yee, Lu-Nguyen, Ngoc, Popplewell, Linda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164894/
https://www.ncbi.nlm.nih.gov/pubmed/29941814
http://dx.doi.org/10.3390/biomedicines6030074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164894/
https://www.ncbi.nlm.nih.gov/pubmed/29941814
http://dx.doi.org/10.3390/biomedicines6030074

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