Cargando…
Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides
Fibrosis results from the excessive accumulation of extracellular matrix in chronically injured tissue. The fibrotic process is governed by crosstalk between many signaling pathways. The search for an effective treatment is further complicated by the fact that there is a degree of tissue-specificity...
Autores principales: | March, James T., Golshirazi, Golnoush, Cernisova, Viktorija, Carr, Heidi, Leong, Yee, Lu-Nguyen, Ngoc, Popplewell, Linda J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164894/ https://www.ncbi.nlm.nih.gov/pubmed/29941814 http://dx.doi.org/10.3390/biomedicines6030074 |
Ejemplares similares
-
Microdystrophin Gene Addition Significantly Improves Muscle Functionality and Diaphragm Muscle Histopathology in a Fibrotic Mouse Model of Duchenne Muscular Dystrophy
por: Cernisova, Viktorija, et al.
Publicado: (2023) -
Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor
por: Kemaladewi, Dwi U, et al.
Publicado: (2014) -
Exon-skipping antisense oligonucleotides for cystic fibrosis therapy
por: Kim, Young Jin, et al.
Publicado: (2022) -
Addressing cancer signal transduction pathways with antisense and siRNA oligonucleotides
por: Juliano, Rudolph L
Publicado: (2020) -
Editorial of the Special Issue: Antisense Therapies
por: Popplewell, Linda J.
Publicado: (2018)