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Loss of Imprinting of Cdkn1c Protects against Age and Diet-Induced Obesity

Cyclin dependent kinase inhibitor 1c (Cdkn1c) is a maternally expressed imprinted gene with roles in embryonic development, post-natal metabolism and behaviour. Using mouse models with altered dosages of Cdkn1c, we have previously identified a role for the gene in promoting brown adipose tissue form...

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Detalles Bibliográficos
Autores principales: Van de Pette, Mathew, Tunster, Simon J., John, Rosalind M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164918/
https://www.ncbi.nlm.nih.gov/pubmed/30213134
http://dx.doi.org/10.3390/ijms19092734