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Targeting TGF-β Signaling in Kidney Fibrosis

Renal fibrosis is the final common pathway of numerous progressive kidney diseases, and transforming growth factor-β (TGF-β) has an important role in tissue fibrosis by up-regulating matrix protein synthesis, inhibiting matrix degradation, and altering cell-cell interaction. Many strategies targetin...

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Detalles Bibliográficos
Autor principal: Isaka, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165001/
https://www.ncbi.nlm.nih.gov/pubmed/30150520
http://dx.doi.org/10.3390/ijms19092532