Efficient Delivery of Macromolecules into Human Cells by Improving the Endosomal Escape Activity of Cell-Penetrating Peptides: Lessons Learned from dfTAT and its Analogs

Cell-penetrating peptides (CPPs) are typically prone to endocytic uptake into human cells. However, they are often inefficient at escaping from endosomes, which limits their ability to deliver cargos into cells. This review highlights the efforts that our laboratory has devoted toward developing CPP...

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Detalles Bibliográficos
Autores principales: Allen, Jason K., Brock, Dakota J., Kondow-McConaghy, Helena M., Pellois, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165022/
https://www.ncbi.nlm.nih.gov/pubmed/29997347
http://dx.doi.org/10.3390/biom8030050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165022/
https://www.ncbi.nlm.nih.gov/pubmed/29997347
http://dx.doi.org/10.3390/biom8030050

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