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Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1

RNA modifications have been implicated in diverse and important roles in all kingdoms of life with over 100 of them present on tRNAs. A prominent modification at the wobble base of four tRNAs is the 7-deaza-guanine derivative queuine which substitutes the guanine at position 34. This exchange is cat...

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Detalles Bibliográficos
Autores principales: Johannsson, Sven, Neumann, Piotr, Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165067/
https://www.ncbi.nlm.nih.gov/pubmed/30149595
http://dx.doi.org/10.3390/biom8030081