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Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice

Molecular factors involved in neuroprotection are key in the design of novel multitarget drugs in aging and neurodegeneration. AVCRI104P3 is a huprine derivative that exhibits potent inhibitory effects on human AChE, BuChE, and BACE-1 activities, as well as on AChE-induced and self-induced Aβ aggreg...

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Detalles Bibliográficos
Autores principales: Relat, Julia, Come, Julio, Perez, Belen, Camps, Pelayo, Muñoz-Torrero, Diego, Badia, Albert, Gimenez-Llort, Lydia, Clos, M. Victòria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165152/
https://www.ncbi.nlm.nih.gov/pubmed/30181440
http://dx.doi.org/10.3390/ijms19092615