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Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice

Molecular factors involved in neuroprotection are key in the design of novel multitarget drugs in aging and neurodegeneration. AVCRI104P3 is a huprine derivative that exhibits potent inhibitory effects on human AChE, BuChE, and BACE-1 activities, as well as on AChE-induced and self-induced Aβ aggreg...

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Detalles Bibliográficos
Autores principales:	Relat, Julia, Come, Julio, Perez, Belen, Camps, Pelayo, Muñoz-Torrero, Diego, Badia, Albert, Gimenez-Llort, Lydia, Clos, M. Victòria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165152/ https://www.ncbi.nlm.nih.gov/pubmed/30181440 http://dx.doi.org/10.3390/ijms19092615

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