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Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification

The protein phosphatase Sit4 has been shown to be required for lipogenesis and resistance against the acetyl-CoA carboxylase inhibitor soraphen A. Since Sit4 is also required for biosynthesis of Elongator dependent tRNA modifications such as 5-methoxycarbonylmethyluridine (mcm(5)U), we investigated...

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Detalles Bibliográficos
Autores principales: Bozaquel-Morais, Bruno Leonardo, Vogt, Leonie, D’Angelo, Valentina, Schaffrath, Raffael, Klassen, Roland, Montero-Lomelí, Mónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165401/
https://www.ncbi.nlm.nih.gov/pubmed/29997346
http://dx.doi.org/10.3390/biom8030049