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Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification
The protein phosphatase Sit4 has been shown to be required for lipogenesis and resistance against the acetyl-CoA carboxylase inhibitor soraphen A. Since Sit4 is also required for biosynthesis of Elongator dependent tRNA modifications such as 5-methoxycarbonylmethyluridine (mcm(5)U), we investigated...
Autores principales: | Bozaquel-Morais, Bruno Leonardo, Vogt, Leonie, D’Angelo, Valentina, Schaffrath, Raffael, Klassen, Roland, Montero-Lomelí, Mónica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165401/ https://www.ncbi.nlm.nih.gov/pubmed/29997346 http://dx.doi.org/10.3390/biom8030049 |
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