Tanshinone IIA Attenuates Insulin Like Growth Factor 1 -Induced Cell Proliferation in PC12 Cells through the PI3K/Akt and MEK/ERK Pathways

The insulin like growth factor 1 (IGF-1) and its receptor (IGF-1R) facilitate tumor proliferation and progression. Tanshinone IIA (TSN) is an active diterpene quinone isolated from the roots of the herbal plant Salvia miltiorrhiza. TSN inhibits the proliferation of various types of cancer cells but...

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Detalles Bibliográficos
Autores principales: Wang, Haitao, Su, Xiaoying, Fang, Jiankang, Xin, Xingan, Zhao, Xia, Gaur, Uma, Wen, Qiang, Xu, Jiangping, Little, Peter J., Zheng, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165471/
https://www.ncbi.nlm.nih.gov/pubmed/30213025
http://dx.doi.org/10.3390/ijms19092719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165471/
https://www.ncbi.nlm.nih.gov/pubmed/30213025
http://dx.doi.org/10.3390/ijms19092719

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