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Isx9 Regulates Calbindin D28K Expression in Pancreatic β Cells and Promotes β Cell Survival and Function

Pancreatic β-cell dysfunction and death contribute to the onset of diabetes, and novel strategies of β-cell function and survival under diabetogenic conditions need to be explored. We previously demonstrated that Isx9, a small molecule based on the isoxazole scaffold, drives neuroendocrine phenotype...

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Detalles Bibliográficos
Autores principales: Pujol, Julien B., Heikkila, Eija, Savoia, Claudia, Hajibeigi, Asghar, De Marchi, Umberto, Battiprolu, Pavan K., Öz, Orhan K., Dioum, El Hadji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165483/
https://www.ncbi.nlm.nih.gov/pubmed/30150605
http://dx.doi.org/10.3390/ijms19092542