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Inhibition of Homophilic Interactions and Ligand Binding of the Receptor for Advanced Glycation End Products by Heparin and Heparin-Related Carbohydrate Structures

Background: Heparin and heparin-related sulphated carbohydrates inhibit ligand binding of the receptor for advanced glycation end products (RAGE). Here, we have studied the ability of heparin to inhibit homophilic interactions of RAGE in living cells and studied how heparin related structures interf...

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Detalles Bibliográficos
Autores principales: Rouhiainen, Ari, Nykänen, Niko-Petteri, Kuja-Panula, Juha, Vanttola, Päivi, Huttunen, Henri J., Rauvala, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165534/
https://www.ncbi.nlm.nih.gov/pubmed/30061484
http://dx.doi.org/10.3390/medicines5030079