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Clinicopathologic Significance of VHL Gene Alteration in Clear-Cell Renal Cell Carcinoma: An Updated Meta-Analysis and Review

The von Hippel-Lindau (VHL) gene is inactivated frequently in sporadic clear-cell renal cell carcinomas (ccRCCs) by genetic alteration (mutation, loss of heterozygosity, or promoter hypermethylation). However, the pathological or prognostic significance of VHL gene alteration has not been well defin...

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Detalles Bibliográficos
Autores principales: Kim, Hyeong Su, Kim, Jung Han, Jang, Hyun Joo, Han, Boram, Zang, Dae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165550/
https://www.ncbi.nlm.nih.gov/pubmed/30149673
http://dx.doi.org/10.3390/ijms19092529