Human IL12RB1 expression is allele-biased and produces a novel IL12 response regulator

Human IL12RB1 is an autosomal gene that is essential for mycobacterial disease resistance and T cell differentiation. Using primary human tissue and PBMCs, we demonstrate that lung and T cell IL12RB1 expression is allele-biased, and the extent to which cells express one IL12RB1 allele is unaffected...

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Detalles Bibliográficos
Autores principales: Reeme, Allison E., Claeys, Tiffany A., Aggarwal, Praful, Turner, Amy J., Routes, John M., Broeckel, Ulrich, Robinson, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165718/
https://www.ncbi.nlm.nih.gov/pubmed/29599514
http://dx.doi.org/10.1038/s41435-018-0023-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165718/
https://www.ncbi.nlm.nih.gov/pubmed/29599514
http://dx.doi.org/10.1038/s41435-018-0023-2

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