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CD16(+)NK-92 and anti-CD123 monoclonal antibody prolongs survival in primary human acute myeloid leukemia xenografted mice

Patients with acute myeloid leukemia (AML) often relapse after initial therapy because of persistence of leukemic stem cells that frequently express the IL-3 receptor alpha chain CD123. Natural killer (NK) cell-based therapeutic strategies for AML show promise and we explore the NK cell lines, NK-92...

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Detalles Bibliográficos
Autores principales: Williams, Brent A., Wang, Xing-Hua, Leyton, Jeffrey V., Maghera, Sonam, Deif, Bishoy, Reilly, Raymond M., Minden, Mark D., Keating, Armand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165813/
https://www.ncbi.nlm.nih.gov/pubmed/29976748
http://dx.doi.org/10.3324/haematol.2017.187385