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CD16(+)NK-92 and anti-CD123 monoclonal antibody prolongs survival in primary human acute myeloid leukemia xenografted mice
Patients with acute myeloid leukemia (AML) often relapse after initial therapy because of persistence of leukemic stem cells that frequently express the IL-3 receptor alpha chain CD123. Natural killer (NK) cell-based therapeutic strategies for AML show promise and we explore the NK cell lines, NK-92...
Autores principales: | Williams, Brent A., Wang, Xing-Hua, Leyton, Jeffrey V., Maghera, Sonam, Deif, Bishoy, Reilly, Raymond M., Minden, Mark D., Keating, Armand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165813/ https://www.ncbi.nlm.nih.gov/pubmed/29976748 http://dx.doi.org/10.3324/haematol.2017.187385 |
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