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Long non-coding RNA PVT1, a molecular sponge for miR-149, contributes aberrant metabolic dysfunction and inflammation in IL-1β-simulated osteoarthritic chondrocytes

Osteoarthritis (OA), a common form of degenerative joint disease, is typified by inflammatory response and the loss of cartilage matrix. Long non-coding RNAs (lncRNAs) are emerging as a new player in gene regulation and exert critical roles in diverse physiologic and pathogenic processes including O...

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Detalles Bibliográficos
Autores principales: Zhao, Yangxue, Zhao, Jiang, Guo, Xufeng, She, Jiang, Liu, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165834/
https://www.ncbi.nlm.nih.gov/pubmed/30126849
http://dx.doi.org/10.1042/BSR20180576