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Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female Zebrafish

It is well established that estrogens regulate female reproduction through estrogen receptors (ERs) in the ovary. However, the precise physiological role of estrogen/ER signaling in reproduction processes remains poorly defined in zebrafish. In this study, we successfully generated an ERα (esr1) mut...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Tang, Haipei, Wang, Le, He, Jianan, Guo, Yin, Liu, Yun, Liu, Xiaochun, Lin, Haoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165881/
https://www.ncbi.nlm.nih.gov/pubmed/30319547
http://dx.doi.org/10.3389/fendo.2018.00567