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Effects of NADPH Oxidase Inhibitors and Mitochondria-Targeted Antioxidants on Amyloid β(1-42)-Induced Neuronal Deaths in Mouse Mixed Cortical Cultures
The Amyloid β peptide (Aβ) is a main component of senile plaques in Alzheimer's disease. Currently, NADPH oxidase (NOX) and mitochondria are considered as primary sources of ROS induced by Aβ. However, the contribution of NOX and mitochondria to Aβ-induced ROS generation has not been well defin...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chonnam National University Medical School
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165920/ https://www.ncbi.nlm.nih.gov/pubmed/30288371 http://dx.doi.org/10.4068/cmj.2018.54.3.159 |