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Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice

BACKGROUND: Several currently available animal models reproduce select behavioral facets of human mania as well as the abnormal glutamatergic neurotransmission and dysregulation of glycogen synthase kinase 3β that accompanies this disease. METHODS: In this study, we addressed the therapeutic potenti...

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Detalles Bibliográficos
Autores principales: Sánchez-Blázquez, Pilar, Cortés-Montero, Elsa, Rodríguez-Muñoz, María, Garzón, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165958/
https://www.ncbi.nlm.nih.gov/pubmed/29860313
http://dx.doi.org/10.1093/ijnp/pyy049