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Identification of novel GLI1 target genes and regulatory circuits in human cancer cells

Hedgehog (HH) signaling is involved in many physiological processes, and pathway deregulation can result in a wide range of malignancies. Glioma‐associated oncogene 1 (GLI1) is a transcription factor and a terminal effector of the HH cascade. Despite its crucial role in tumorigenesis, our understand...

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Detalles Bibliográficos
Autores principales: Diao, Yumei, Rahman, Mohammed Ferdous‐Ur, Vyatkin, Yuri, Azatyan, Ani, St. Laurent, Georges, Kapranov, Philipp, Zaphiropoulos, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166001/
https://www.ncbi.nlm.nih.gov/pubmed/30098229
http://dx.doi.org/10.1002/1878-0261.12366