ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin‐1‐dependent invasiveness, and these effects can be ameliorated using the BET inhibitor apabetalone

At the time of diagnosis, 20% of patients with colorectal cancer present metastasis. Among individuals with primary lesions, 50% of them will develop distant tumours with time. Therefore, early diagnosis and prediction of aggressiveness is crucial for therapy design and disease prognosis. Tumoral ce...

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Detalles Bibliográficos
Autores principales: Aguirre‐Portolés, Cristina, Feliu, Jaime, Reglero, Guillermo, Ramírez de Molina, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166002/
https://www.ncbi.nlm.nih.gov/pubmed/30098223
http://dx.doi.org/10.1002/1878-0261.12367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166002/
https://www.ncbi.nlm.nih.gov/pubmed/30098223
http://dx.doi.org/10.1002/1878-0261.12367

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