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Presence of few PD‐1‐expressing tumor‐infiltrating immune cells is a potential predictor of improved response to salvage chemotherapy following nivolumab for non‐small cell lung cancer: An exploratory case series

BACKGROUND: The combination of PD‐1 inhibitors and cytotoxic drugs is reported to enhance anti‐tumor activity in non‐small cell lung cancer; however, the underlying synergistic mechanisms remain uncertain. This retrospective case series was designed to investigate objective response and survival rat...

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Detalles Bibliográficos
Autores principales: Ogawara, Daiki, Soda, Hiroshi, Tomono, Hiromi, Iwasaki, Keisuke, Hara, Takuya, Jinnai, Saeko, Funayama, Takatomo, Okuno, Daisuke, Taniguchi, Hirokazu, Yoshida, Masataka, Harada, Tatsuhiko, Umemura, Asuka, Fukuda, Yuichi, Yamaguchi, Hiroyuki, Mukae, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166078/
https://www.ncbi.nlm.nih.gov/pubmed/30126069
http://dx.doi.org/10.1111/1759-7714.12844