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Interferon-free treatment for hepatitis C virus infection induces normalization of extrahepatic type I interferon signaling

BACKGROUND/AIMS: Hepatitis C virus (HCV) replicates in the peripheral blood mononuclear cells (PBMCs), leading to the production of type I interferons (IFNs). It is well known that the gene expression profile of PBMC is similar to that of the liver. The present study explored the dynamic gene expres...

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Detalles Bibliográficos
Autores principales: Sung, Pil Soo, Lee, Eun Byul, Park, Dong Jun, Lozada, Angelo, Jang, Jeong Won, Bae, Si Hyun, Choi, Jong Young, Yoon, Seung Kew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166108/
https://www.ncbi.nlm.nih.gov/pubmed/29526079
http://dx.doi.org/10.3350/cmh.2017.0074