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Histone H2A‐H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatin

The eukaryotic replisome disassembles parental chromatin at DNA replication forks, but then plays a poorly understood role in the re‐deposition of the displaced histone complexes onto nascent DNA. Here, we show that yeast DNA polymerase α contains a histone‐binding motif that is conserved in human P...

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Detalles Bibliográficos
Autores principales: Evrin, Cecile, Maman, Joseph D, Diamante, Aurora, Pellegrini, Luca, Labib, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166128/
https://www.ncbi.nlm.nih.gov/pubmed/30104407
http://dx.doi.org/10.15252/embj.201899021