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Plasmodial Kinase Inhibitors: License to Cure?

[Image: see text] Advances in the genetics, function, and stage-specificity of Plasmodium kinases has driven robust efforts to identify targets for the design of antimalarial therapies. Reverse genomics following phenotypic screening against Plasmodia or related parasites has uncovered vulnerable ki...

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Detalles Bibliográficos
Autores principales: Cabrera, Diego González, Horatscheck, André, Wilson, Colin R., Basarab, Greg, Eyermann, Charles J., Chibale, Kelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166223/
https://www.ncbi.nlm.nih.gov/pubmed/29771541
http://dx.doi.org/10.1021/acs.jmedchem.8b00329