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Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment

Chemotherapy-induced cognitive impairment (CICI) is a commonly reported neurotoxic side effect of chemotherapy, occurring in up to 75% cancer patients. CICI manifests as decrements in working memory, executive functioning, attention, and processing speed, and greatly interferes with patients’ daily...

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Detalles Bibliográficos
Autores principales: Ma, Jiacheng, Huo, XiaoJiao, Jarpe, Matthew B., Kavelaars, Annemieke, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166273/
https://www.ncbi.nlm.nih.gov/pubmed/30270813
http://dx.doi.org/10.1186/s40478-018-0604-3