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Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment

Chemotherapy-induced cognitive impairment (CICI) is a commonly reported neurotoxic side effect of chemotherapy, occurring in up to 75% cancer patients. CICI manifests as decrements in working memory, executive functioning, attention, and processing speed, and greatly interferes with patients’ daily...

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Detalles Bibliográficos
Autores principales:	Ma, Jiacheng, Huo, XiaoJiao, Jarpe, Matthew B., Kavelaars, Annemieke, Heijnen, Cobi J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166273/ https://www.ncbi.nlm.nih.gov/pubmed/30270813 http://dx.doi.org/10.1186/s40478-018-0604-3

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