High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure

BACKGROUND: Humanity has become largely dependent on artemisinin derivatives for both the treatment and control of malaria, with few alternatives available. A Plasmodium falciparum phenotype with delayed parasite clearance during artemisinin-based combination therapy has established in Southeast Asi...

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Detalles Bibliográficos
Autores principales: Tyagi, Rajeev K., Gleeson, Patrick J., Arnold, Ludovic, Tahar, Rachida, Prieur, Eric, Decosterd, Laurent, Pérignon, Jean-Louis, Olliaro, Piero, Druilhe, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166299/
https://www.ncbi.nlm.nih.gov/pubmed/30269689
http://dx.doi.org/10.1186/s12916-018-1156-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166299/
https://www.ncbi.nlm.nih.gov/pubmed/30269689
http://dx.doi.org/10.1186/s12916-018-1156-x

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