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Screening and analysis of acetyl-cholinesterase (AChE) inhibitors in the context of Alzheimer's disease

Acetyl-cholinesterase enzyme (AChE) is a known target for identifying potential inhibitors against Alzheimer diseases (AD). Therefore, it is of interest to screen AChE with the CNS-BBB database. An AChE enzyme is a member of hydrolase family is activated by acetylcholine (ACh), so, targeting the ACh...

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Detalles Bibliográficos
Autores principales: Khan, Mohd. Babu, Palaka, Bhagath Kumar, Sapam, Tuleshwori Devi, Subbarao, Naidu, Ampasala, Dinakara Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166398/
https://www.ncbi.nlm.nih.gov/pubmed/30310249
http://dx.doi.org/10.6026/97320630014414