Cargando…

Screening and analysis of acetyl-cholinesterase (AChE) inhibitors in the context of Alzheimer's disease

Acetyl-cholinesterase enzyme (AChE) is a known target for identifying potential inhibitors against Alzheimer diseases (AD). Therefore, it is of interest to screen AChE with the CNS-BBB database. An AChE enzyme is a member of hydrolase family is activated by acetylcholine (ACh), so, targeting the ACh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Mohd. Babu, Palaka, Bhagath Kumar, Sapam, Tuleshwori Devi, Subbarao, Naidu, Ampasala, Dinakara Rao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2018
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166398/ https://www.ncbi.nlm.nih.gov/pubmed/30310249 http://dx.doi.org/10.6026/97320630014414

Ejemplares similares

Purification and characterization of lipoxygenase from mung bean (Vigna radiata L.) germinating seedlings
por: Aanangi, Raveendra, et al.
Publicado: (2016)

Designing novel inhibitors against Mycobacterium tuberculosis FadA5 (acetyl-CoA acetyltransferase) by virtual screening of known anti-tuberculosis (bioactive) compounds
por: Jaiswal, Atul Kumar, et al.
Publicado: (2018)

High Throughput Virtual Screening to Identify Novel natural product Inhibitors for MethionyltRNA-Synthetase of Brucella melitensis
por: Kumari, Madhulata, et al.
Publicado: (2017)

Predictive inference on cytoplasmic and mitochondrial thioredoxin peroxidases in the highly radioresistant Lepidopteran insect Spodoptera frugiperda
por: Hambarde, Shashank, et al.
Publicado: (2010)

Molecular docking of fisetin with AD associated AChE, ABAD and BACE1 proteins
por: Dash, Raju, et al.
Publicado: (2014)

Virtual screening of plant derived compounds for aldose reductase inhibition using molecular docking
por: Muppalaneni, Naresh Babu, et al.
Publicado: (2012)

Computational Analysis of N-acetyl transferase in Tribolium castaneum
por: Singh, Kailash, et al.
Publicado: (2013)

Prediction of the three-dimensional structure of aflatoxin of Aspergillus flavus by homology modelling
por: Kasoju, Aruna, et al.
Publicado: (2012)

Screening of inhibitors for S130G inhibitor resistant mutants of TEM type beta-lactamase
por: Baig, Mohd Hassan, et al.
Publicado: (2012)

Binding of activated isoniazid with acetyl-CoA carboxylase from Mycobacterium tuberculosis
por: Unissa, Ameeruddin Nusrath, et al.
Publicado: (2011)

Molecular docking and virtual screening for novel protein tyrosine phosphatase 1B (PTP1B) inhibitors
por: Rao, Pasupuleti Sreenivasa, et al.
Publicado: (2012)

Protein interaction network for Alzheimer's disease using computational approach
por: Rao, V Srinivasa, et al.
Publicado: (2013)

Virtual screening of RAGE inhibitors using molecular docking
por: Devi Alaparthi, Malini, et al.
Publicado: (2016)

Molecular modeling and analysis of human and plant endo-β-N-acetyl- glucosaminidases for mutations effects on function
por: Choragudi, Shechinah Felice, et al.
Publicado: (2014)

Molecular Docking and Pharmacological Investigations of Rivastigmine-Fluoxetine and Coumarin–Tacrine hybrids against Acetyl Choline Esterase
por: Babitha, Pallikkara Pulikkal, et al.
Publicado: (2015)

Prediction of Protein Acetylation Sites using Kernel Naive Bayes Classifier Based on Protein Sequences Profiling
por: Ahmed, Md. Shakil, et al.
Publicado: (2018)

Unraveling Alzheimer’s: Making Sense of the Relationship between Diabetes and Alzheimer’s Disease(1)
por: Schilling, Melissa A.
Publicado: (2016)

Alzheimer’s Amyloidopathy: An Alternative Aspect
por: Regland, Björn, et al.
Publicado: (2019)

Anticoagulants for Treatment of Alzheimer’s Disease
por: Grossmann, Klaus
Publicado: (2020)

A novel sequence and context based method for promoter recognition
por: P, Umesh, et al.
Publicado: (2014)

The Adult Neurogenesis Theory of Alzheimer’s Disease
por: Abbate, Carlo
Publicado: (2023)

Alzheimer's disease and Type 2 diabetes mellitus: the cholinesterase connection?
por: Allam, Appa Rao, et al.
Publicado: (2006)

The DNA Replication Stress Hypothesis of Alzheimer's Disease
por: Yurov, Yuri B., et al.
Publicado: (2012)

The GABA–Working Memory Relationship in Alzheimer’s Disease
por: Mandal, Pravat K., et al.
Publicado: (2017)

The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets
por: Norwitz, Nicholas G., et al.
Publicado: (2022)

Phylogenetic analysis of surface proteins of novel H1N1 virus isolated from 2009 pandemic
por: Danishuddin, Mohd, et al.
Publicado: (2009)

Virtual screening and in vitro assay of potential drug like inhibitors from spices against Glutathione-S-Transferase of Meloidogyne incognita
por: Babu, Rosana O, et al.
Publicado: (2012)

Virtual screening for novel COX-2 inhibitors using the ZINC database
por: Sudha, Kotaprolu Naga, et al.
Publicado: (2008)

Do Microglia Default on Network Maintenance in Alzheimer’s Disease?
por: Southam, Katherine A., et al.
Publicado: (2016)

Structure based molecular inhibition of Caspase-8 for treatment of multi-neurodegenerative diseases using known natural compounds
por: Ahmad, Khurshid, et al.
Publicado: (2014)

Inferences from the ADMET analysis of predicted inhibitors to Follicle Stimulating Hormone in the context of infertility
por: Bhogireddy, Narasimharao, et al.
Publicado: (2013)

Molecular docking analysis of known flavonoids as duel COX-2 inhibitors in the context of cancer
por: Dash, Raju, et al.
Publicado: (2015)

Neuroendocrine immunity in patients with Alzheimer's disease: toward translational epigenetics
por: Chiappelli, Francesco, et al.
Publicado: (2007)

The Blood-Brain Barrier and Microvascular Water Exchange in Alzheimer's Disease
por: Anderson, Valerie C., et al.
Publicado: (2011)

Detection of severity in Alzheimer's disease (AD) using computational modeling
por: Kim, Hyunjo
Publicado: (2018)

Transgenerational Interaction of Alzheimer’s Disease with Schizophrenia through Amyloid Evolvability
por: Takamatsu, Yoshiki, et al.
Publicado: (2019)

Neurogenesis Makes a Crucial Contribution to the Neuropathology of Alzheimer’s Disease
por: Young, John K.
Publicado: (2020)

A New Hypothesis for Alzheimer’s Disease: The Lipid Invasion Model
por: Rudge, Jonathan D’Arcy
Publicado: (2022)

Norepinephrine May Oppose Other Neuromodulators to Impact Alzheimer’s Disease
por: Fitzgerald, Paul J.
Publicado: (2021)

A comprehensive analysis of LACK (Leishmania homologue of receptors for activated C kinase) in the context of Visceral Leishmaniasis
por: Sinha, Sukrat, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_mg58sk5sgi8dski7cnnfs5rfot