Purinergic Vasotoxicity: Role of the Pore/Oxidant/K(ATP) Channel/Ca(2+) Pathway in P2X(7)-Induced Cell Death in Retinal Capillaries

P2X(7) receptor/channels in the retinal microvasculature not only regulate vasomotor activity, but can also trigger cells in the capillaries to die. While it is known that this purinergic vasotoxicity is dependent on the transmembrane pores that form during P2X(7) activation, events linking pore for...

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Detalles Bibliográficos
Autores principales: Shibata, Maho, Ishizaki, Eisuke, Zhang, Ting, Fukumoto, Masanori, Barajas-Espinosa, Alma, Li, Tong, Puro, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166475/
https://www.ncbi.nlm.nih.gov/pubmed/30288454
http://dx.doi.org/10.3390/vision2030025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166475/
https://www.ncbi.nlm.nih.gov/pubmed/30288454
http://dx.doi.org/10.3390/vision2030025

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